{"id":280,"date":"2015-03-17T23:42:19","date_gmt":"2015-03-17T23:42:19","guid":{"rendered":"http:\/\/centredebienetreholistique.com\/?p=280"},"modified":"2019-11-27T03:30:24","modified_gmt":"2019-11-27T03:30:24","slug":"lananas-est-superieur-a-la-chimie-5-fu-5-fluouracil","status":"publish","type":"post","link":"https:\/\/centredebienetreholistique.com\/?p=280","title":{"rendered":"L’ananas est sup\u00e9rieur \u00e0 la chimio 5-FU (5-fluouracil)"},"content":{"rendered":"
Une \u00e9quipe de chercheurs et scientiques on publi\u00e9 dans la revue Planta Medica les r\u00e9sultats d’extraits d’annas comme \u00e9tant sup\u00e9rieurs \u00e0 l’agent cytotoxique 5-fluorauracil in vivo (i.e., exp\u00e9rimentation animale, voir l’\u00e9tude ci-dessous). La chimio 5-FU est un poison non seulement pour les cellules canc\u00e9reuses, mais aussi pour toutes les autres cellules humaines qui se divisent rapidement (par ex, les cellules immunitaires, les cellules des cheveux, des intestins etc), vu que le m\u00e9canisme d’action de cette drogue cible et inhibe la synth\u00e8se RNA et ses enzymes de reproduction. A contrario, \u00a0les mol\u00e9cules naturelles comme les enzymes bromelaines des ananas sont g\u00e9n\u00e9ralement dot\u00e9es d’une cytotoxicit\u00e9 s\u00e9lective,<\/strong> \u00a0poussant les cellules handicap\u00e9es comme les cellules canc\u00e9reuses \u00e0 s’\u00e9liminer d’elle memes (via le m\u00e9canisme de l’apoptose), tout en gardant l’ensemble des autres cellules intact. \u00a0Pire, la chimio cytotoxique a tendance \u00e0 renforcer la chimio-r\u00e9sistance ainsi que les cellules canc\u00e9reuses souches, lesquelles deviennent encore plus agressives, tout en profitant pour se disperser au travers du corps, nonobstant une certain r\u00e9duction tumorale de l’excroissance primaire.<\/h5>\n
\"pineappleCRoK\"<\/a>Attribution photo :\u00a0 Creative Commons \u00a0et Wikipedia<\/h6>\n

 <\/p>\n

Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24.<\/p>\n

In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain.
\nB\u00e1ez R1, Lopes MT, Salas CE, Hern\u00e1ndez M.<\/p>\n

Abstract<\/p>\n

Stem bromelain (EC 3.4.22.32) is a major cysteine proteinase, isolated from pineapple ( Ananas comosus) stem. Its main medicinal use is recognized as digestive, in vaccine formulation, antitumoral and skin debrider for the treatment of burns. To verify the identity of the principle in stem fractions responsible for the antitumoral effect, we isolated bromelain to probe its pharmacological effects. The isolated bromelain was obtained from stems of adult pineapple plants by buffered aqueous extraction and cationic chromatography. The homogeneity of bromelain was confirmed by reverse phase HPLC, SDS-PAGE and N-terminal sequencing. The in vivo antitumoral\/antileukemic activity was evaluated using the following panel of tumor lines: P-388 leukemia, sarcoma (S-37), Ehrlich ascitic tumor (EAT), Lewis lung carcinoma (LLC), MB-F10 melanoma and ADC-755 mammary adenocarcinoma. Intraperitoneal administration of bromelain (1, 12.5, 25 mg\/kg), began 24 h after tumor cell inoculation in experiments in which 5-fluorouracil (5-FU, 20 mg\/kg) was used as positive control. The antitumoral activity was assessed by the survival increase (% survival index) following various treatments. With the exception of MB-F10 melanoma, all other tumor-bearing animals had a significantly increased survival index after bromelain treatment. The largest increase ( approximately 318 %) was attained in mice bearing EAT ascites and receiving 12.5 mg\/kg of bromelain. This antitumoral effect was superior to that of 5-FU, whose survival index was approximately 263 %, relative to the untreated control<\/strong>. Bromelain significantly reduced the number of lung metastasis induced by LLC transplantation, as observed with 5-FU. The antitumoral activity of bromelain against S-37 and EAT, which are tumor models sensitive to immune system mediators, and the unchanged tumor progression in the metastatic model suggests that the antimetastatic action results from a mechanism independent of the primary antitumoral effect.<\/p>\n

\"LOGOcentrePy\"<\/a><\/p>\n

Copyright: \u00a0Centre Pyr\u00e9n\u00e9en de Bien-Etre Holistique<\/p>\n

Toutes les informations contenues dans les blogs, articles et \u00e9tudes de ce Blog sont pr\u00e9sent\u00e9es \u00e0 titre \u00e9ducatif et ne peuvent pas \u00eatre interpr\u00e9t\u00e9es comme avis m\u00e9dical<\/p>\n","protected":false},"excerpt":{"rendered":"

Une \u00e9quipe de chercheurs et scientiques on publi\u00e9 dans la revue Planta Medica les r\u00e9sultats d’extraits d’annas comme \u00e9tant sup\u00e9rieurs \u00e0 l’agent cytotoxique 5-fluorauracil in vivo (i.e., exp\u00e9rimentation animale, voir l’\u00e9tude ci-dessous). La chimio 5-FU est un poison non seulement …<\/p>\n

L’ananas est sup\u00e9rieur \u00e0 la chimio 5-FU (5-fluouracil)<\/span> Read More »<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","footnotes":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4FfFc-4w","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":311,"url":"https:\/\/centredebienetreholistique.com\/?p=311","url_meta":{"origin":280,"position":0},"title":"Rendez-vous \u201cCanc\u00e9rologie\u201d avec le chercheur Robert Weinberg","author":"centredebienetreholistique","date":"March 29, 2015","format":false,"excerpt":"LES TRAVAUX DU PROFESSEUR WEINBERG EN CANC\u00c9ROGEN\u00c8SE: \u00a0Via les deux vid\u00e9os ci-dessous du Professeur Robert Weinberg, l\u2019une des \u2018autorit\u00e9s am\u00e9ricaines et mondiales digne d\u2019un Nobel et auteur du best seller \"Biology of Cancer\", vous pourrez mieux comprendre ou va la recherche en mati\u00e8re de canc\u00e9rologie. Dans le documentaire, Holistic Oncology\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1267,"url":"https:\/\/centredebienetreholistique.com\/?p=1267","url_meta":{"origin":280,"position":1},"title":"Le pamplemousse peut \u00eatre b\u00e9n\u00e9fique pour la r\u00e9paration des mutations g\u00e9n\u00e9tiques, le cancer, maladies m\u00e9taboliques et le vieillissement pr\u00e9coce de la peau","author":"centredebienetreholistique","date":"August 12, 2016","format":false,"excerpt":"Dans ce post, je passerais en revue quelques preuves qui confirment que le pamplemousse contient des mol\u00e9cules qui sont capables \u00a0de r\u00e9parer plusieurs types de mutations g\u00e9n\u00e9tiques \u00a0(SECTION A), \u00a0de combattre le cancer\u00a0(SECTION B)\u00a0ainsi que plusieurs d\u00e9sordres m\u00e9taboliques et le vieillissement pr\u00e9coce de la peau\u00a0(SECTION C). SECTION A R\u00c9PARATION DES\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2973,"url":"https:\/\/centredebienetreholistique.com\/?p=2973","url_meta":{"origin":280,"position":2},"title":"Atelier “immunit\u00e9, pand\u00e9mies et COVID 19” du Stage d’\u00e9t\u00e9 sur la Long\u00e9vit\u00e9 Optimale","author":"centredebienetreholistique","date":"March 28, 2020","format":false,"excerpt":"Descriptif de l'Atelier Cet \u00e9t\u00e9, si tout se passe bien et si nous avions assez de stagiaires, le Centre de bien-entre holistique enseignera un atelier \"immunit\u00e9 et pand\u00e9mie\". Dams cette perspective, \u00a0plusieurs protocoles holistiques qui peuvent avoir raison du SARS COV-2 et d'autres virus seront analys\u00e9s. On \u00e9tudiera aussi les\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1048,"url":"https:\/\/centredebienetreholistique.com\/?p=1048","url_meta":{"origin":280,"position":3},"title":"La Hug Th\u00e9rapie, productrice d’ocytocine et d’anandamide, fait partie de la M\u00e9decine Holistique","author":"centredebienetreholistique","date":"December 26, 2015","format":false,"excerpt":"En mettant en oeuvre la \"hug therapy\", (ie, th\u00e9rapie de l'accolade, de l'\u00e9treinte), des scientifiques universitaires am\u00e9ricains ont d\u00e9montr\u00e9 que\u00a0l'hormone ocytocine (1) se mobilise en actionnant les r\u00e9cepteurs de notre syst\u00e8me endocannabinoidal, tout en vivifiant une autre mol\u00e9cule qui s'appelle la \u201cbliss molecule\u201d ou l'anandamide. (2) Ce faisant, les sentiments\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":9888,"url":"https:\/\/centredebienetreholistique.com\/?p=9888","url_meta":{"origin":280,"position":4},"title":"Vis medicatrix naturae et la M\u00e9decine du Shinrin-Yoku (Forest Bathing) au Centre M\u00e9diterran\u00e9en Holistique","author":"centredebienetreholistique","date":"April 28, 2021","format":false,"excerpt":"Plusieurs \u00e9tudes publi\u00e9es dans des journaux scientifiques reconnus ont montr\u00e9 que les terpenes et phytoncides \u00a0(huiles essentielles des forets, en particulier les\u00a0isoprenes, alpha-pinenes, et beta-pinenes) ainsi que microbes et virus et leurs m\u00e9tabolites dans l'air (1)\u00a0des forets biodiversif\u00e9es impactent de fa\u00e7on th\u00e9rapeutique (quantifiable) la sant\u00e9 humaine, y compris en mati\u00e8re\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1246,"url":"https:\/\/centredebienetreholistique.com\/?p=1246","url_meta":{"origin":280,"position":5},"title":"La vaccination vue au travers du prisme du microbiome, de la science et de la m\u00e9decine holistique.","author":"centredebienetreholistique","date":"July 11, 2016","format":false,"excerpt":"Suite \u00e0 la radiation de toute \u00e9vidence abusive d'Henri Joyeux, professeur de canc\u00e9rologie, par le Conseil National de l'Ordre des M\u00e9decins, (cr\u00e9e par l'Etat de Vichy), je viens d'\u00e9couter une partie du d\u00e9bat vaccin fran\u00e7ais et je constate plusieurs carences par rapport aux d\u00e9bats scientifiques am\u00e9ricains. LE D\u00c9BAT SCIENTIFIQUE AM\u00c9RICAIN\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/posts\/280"}],"collection":[{"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=280"}],"version-history":[{"count":8,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/posts\/280\/revisions"}],"predecessor-version":[{"id":2895,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=\/wp\/v2\/posts\/280\/revisions\/2895"}],"wp:attachment":[{"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/centredebienetreholistique.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}